BiliAid Neonatal Hyperbilirubinemia Management

Enter completed weeks only (e.g., for 37.5 or 37 3/7 weeks, enter 37).
Must be equal to or greater than 35 weeks gestational age.

Age in hours when blood was drawn or TCB performed.

Leave blank if entering date and time of birth and bilirubin collection.

For multiple collection times, enter values separated by commas (e.g., 24, 48, 72).

May leave blank if entering age in hours at the time of bilirubin collection.

May leave blank if entering age in hours at the time of bilirubin collection.

For multiple bilirubin values, enter values separated by commas (e.g., 6, 12, 14 for values of 6, 12, and 14 mg/dL).

TSB: Total Serum Bilirubin via blood.
TCB: Transcutaneous Bilirubin.
If multiple bilirubin levels are entered, specify the method of collection for the latest level.
Select ‘Yes’ if the neonate has sepsis or is suspected of having sepsis.

Clinical instability refers to a significant change in the Neonate's health status, such as difficulty breathing or changes in heart rate.

If an infant’s DAT is known to be positive only to anti-Rh(D) because the mother received RhIG during pregnancy and the mother was known not to have Rh(D) antibodies before receiving RhIG, the infant can be treated as if the infant is DAT negative. However, any infant with a positive DAT attributable to an antibody other than anti-Rh(D) following maternal receipt of RhIG should be considered to be DAT positive.

Glucose-6-phosphate dehydrogenase (G6PD) deficiency, an X-linked recessive enzymopathy that decreases protection against oxidative stress, is now recognized as one of the most important causes of hazardous hyperbilirubinemia leading to kernicterus in the United States and across the globe.

Low serum albumin can increase the risk of neurotoxicity because of the greater availability of unbound bilirubin (ie, bilirubin not bound to albumin).

ETOc is end-tidal CO2 in breath corrected for ambient carbon monoxide. A high ETCOc level may indicate hemolysis.

AAP 2022 Guideline Revision: Managing Newborn Hyperbilirubinemia

Highlights of the revised clinical practice guideline for infants 35 or more weeks of gestation. For more information, click on the bold items.

Reference article: Pediatrics (2022) 150 (3): e2022058859.